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Isolates Solid Organs Enabling Delivery
of Therapeutic Agents
Current focus area and additional organs planned
Targeted Drug Delivery System fi_508836 (2)
Kidneys
  • Proof of concept achieved
  • Kidney DiNATEQ™ LRP established in-vivo in a large animal model
Targeted Drug Delivery System fi_508837 (2)
Heart
  • Proof of concept achieved
  • Excellent safety profile of the perfusion for up to 2 hours
Targeted Drug Delivery System fi_1546081 (2)
Lungs
  • Preparing proof of concept
  • Segmental delivery demonstrated
Targeted Drug Delivery System fi_508849 (2)
Liver, Pancreas
  • Preparing proof of concept
  • Design concepts identified
DiNATEQ™ LRP System Enables the Direct Delivery
of Multiple Modalities to Address Numerous Diseases
Targeted Drug Delivery System Group 21912 (1)
How DiNATEQ™ LRP System Works
Direct route of administration to target organ
Large number of payload opportunity
Application to numerous organs and diseases
Targeted Drug Delivery System fi_9709201
Gene Replacement
Targeted Drug Delivery System fi_14784220
Small Molecules
Targeted Drug Delivery System fi_14784207
Gene Editing
 fi_11827711
ASOs/RNA
 fi_11827736
Biologics
 fi_508837 (3)
Heart
 fi_508854 (2)
Intestines
 fi_508849 (3)
Liver
 fi_109827
Brain
 fi_5726783 (2)
Stomach
 fi_10172680 (2)
Pancreas
 fi_1546081 (3)
Lungs
 fi_508836 (3)
Kidneys
 fi_7077857 (2)
Bladder
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