Isolates Solid Organs Enabling Delivery
of Therapeutic Agents
of Therapeutic Agents
Current focus area and additional organs planned
fi_508836 (2)
Kidneys
- Proof of concept achieved
- Kidney DiNATEQ™ LRP established in-vivo in a large animal model
fi_508837 (2)
Heart
- Proof of concept achieved
- Excellent safety profile of the perfusion for up to 2 hours
fi_1546081 (2)
Lungs
- Preparing proof of concept
- Segmental delivery demonstrated
fi_508849 (2)
Liver, Pancreas
- Preparing proof of concept
- Design concepts identified
DiNATEQ™ LRP System Enables the Direct Delivery
of Multiple Modalities to Address Numerous Diseases
of Multiple Modalities to Address Numerous Diseases
Group 21912 (1)
How DiNATEQ™ LRP System Works
Direct route of administration to target organ
Direct route of administration to target organ
Large number of payload opportunity
Application to numerous organs and diseases
fi_9709201
Gene Replacement
fi_14784220
Small Molecules
fi_14784207
Gene Editing
fi_11827711
ASOs/RNA
fi_11827736
Biologics
fi_508837 (3)
Heart
fi_508854 (2)
Intestines
fi_508849 (3)
Liver
fi_109827
Brain
fi_5726783 (2)
Stomach
fi_10172680 (2)
Pancreas
fi_1546081 (3)
Lungs
fi_508836 (3)
Kidneys
fi_7077857 (2)
Bladder
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