Isolates Solid Organs Enabling Delivery
of Therapeutic Agents
of Therapeutic Agents
Current focus area and additional organs planned
Kidneys
- Proof of concept achieved
- Kidney DiNATEQ™ LRP established in-vivo in a large animal model
Heart
- Proof of concept achieved
- Excellent safety profile of the perfusion for up to 2 hours
Lungs
- Preparing proof of concept
- Segmental delivery demonstrated
Liver, Pancreas
- Preparing proof of concept
- Design concepts identified
DiNATEQ™ LRP System Enables the Direct Delivery
of Multiple Modalities to Address Numerous Diseases
of Multiple Modalities to Address Numerous Diseases
How DiNATEQ™ LRP System Works
Direct route of administration to target organ
Direct route of administration to target organ
Large number of payload opportunity
Application to numerous organs and diseases
Gene Replacement
Small Molecules
Gene Editing
ASOs/RNA
Biologics
Heart
Intestines
Liver
Brain
Stomach
Pancreas
Lungs
Kidneys
Bladder
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